This project addresses a critical, currently underserved need in pediatric mental health care: the lack of personalized, evidence-informed approaches to medication prescribing. Specifically, we aim to bridge the gap between existing pharmacogenetic (PGx) knowledge and its practical application in Alberta’s youth mental health services. This project builds on the foundational work of the initial Pharmacogenetic-Supported Prescribing in Kids (PGx-SParK, 2020-2025) project and will develop and evaluate a sustainable, Alberta-specific strategy to incorporate PGx testing into standard pediatric mental health care. This initiative is not only timely but necessary, as it aligns with emerging precision medicine approaches and health system priorities aimed at improving outcomes, reducing unnecessary costs, and advancing health equity.
Develop and pilot a made-in-Alberta implementation strategy that will serve as a blueprint for province-wide adoption.
Evaluate the feasibility and acceptability of PGx testing in a public healthcare setting.
Establish a PGx testing implementation strategy that with minimal adaptation could be expanded to other therapeutic areas relevant to youth health, including neurology, cardiology, oncology, and gastroenterology.
Aged 6 – 24 years
Located in Alberta
Has an Alberta Health Number
Initiating or changing a psychiatric medication with a PGx indication
COMING SOON
Dr. Chad Bousman, MPH, PhD, Professor, Medical Genetics, University of Calgary
Dr. Paul Arnold, MD, PhD, FRCPC, Director, Mathison Centre for Mental Health Research & Education; Alberta Innovates Health Solutions (AIHS) Translational Health Chair in Child and Youth Mental Health; Professor, Departments of Psychiatry and Medical Genetics
Dr. Ahmad Abdel Latif, PhD, Assistant Professor, Department of Electrical and Software Engineering, Schulich School of Engineering, University of Calgary.
Dr. Adrian Box, MD, PhD, Director, Molecular Pathology Laboratory, Alberta Precision Laboratories; Clinical Assistant Professor, Department of Pathology and Laboratory Medicine
Dr. Dennis Bulman, PhD, Medical Scientific Director of Genetics and Genomics, Alberta Public Laboratories Clinical Professor, Departments of Medical Genetics and Pathology and Laboratory Medicine.
Rekha Jabbal, BSc (Pharm), MA, Pharmacy Clinical Practice Leader at Alberta Health Services
Dr. Mark Yarema, MD, FRCPC, Lead, Calgary Clinical Pharmacology Consultation Service and Section Chief, Clinical Pharmacology and Toxicology, Alberta Health Services
Madison Heintz, MSW, RSW
Sarker M Shaheen, MSc, MBA, PM
Ryden McCloud-Trenchard, BS
University of Calgary
Alberta Children's Hospital Research Institute
Alberta Precision Laboratories
Alberta Health Services, Ambulatory Pharmacy
Acute Care Alberta Child Health Program
Mathison Centre for Mental Health Research & Education
Owerko Centre
Calgary Clinical Pharmacology Consultation Service